Citation  Results 
Beasley et al11  Continuation

Burke et al12  Pregnancy: (I) 3/322; (C) 4/290, p=0.71. Side effects or adverse events
Month 3: (I) 91/355 (26%); (C) 110/342 (32%) Month 6: (I) 55/324 (17%); (C) 56/254 (22%) Month 9: (I) 41/306 (13%); (C) 38/213 (18%)
Month 3: (I) 40/91 (44%); (C) 54/110 (49%) Month 6: (I) 27/55 (49%); (C) 25/56 (45%) Month 9: (I) 19/41 (46%); (C) 12/38 (32%)
Month 3: (I) 33/91 (36%); (C) 48/110 (44%) Month 6: (I) 9/55 (16%); (C) 14/56 (25%) Month 9: (I) 7/41 (17%); (C) 12/38 (32%)
Month 3: (I) 29/91 (32%); (C) 48/110 (44%) Month 6: (I) 17/55 (31%); (C) 19/56 (34%) Month 9: (I) 13/41 (32%); (C) 14/38 (37%)
Month 3: (I) 38/91 (42%); (C) 27/110 (25%) Month 6: (I) 19/55 (35%); (C) 13/56 (23%) Month 9: (I) 16/41 (39%); (C) 5/38 (13%)
Month 3: (I) 32/91 (35%); (C) 32/110 (29%) Month 6: (I) 28/55 (51%); (C) 22/56 (39%) Month 9: (I) 24/41 (59%); (C) 14/38 (37%)
Month 3: (I) 27/91 (30%); (C) 33/110 (30%) Month 6: (I) 20/55 (36%); (C) 21/56 (38%) Month 9: (I) 16/41 (39%); (C) 17/38 (45%)
Month 3: (I) 26/91 (29%); (C) 20/110 (18%) Month 6: (I) 13/55 (24%); (C) 16/56 (29%) Month 9: (I) 8/41 (20%); (C) 8/38 (21%)
Month 3: (I) 15/91 (16%); (C) 15/110 (14%) Month 6: (I) 9/55 (16%); (C) 9/56 (16%) Month 9: (I) 5/41 (12%); (C) 11/38 (29%)
Month 3: (I) 5/91 (5%); (C) 9/110 (8%) Month 6: (I) 7/55 (13%); (C) 8/56 (14%) Month 9: (I) 1/41 (2%); (C) 11/38 (29%) 
Continuation
Month 0: (I) 1/364; (C) 0/367 Month 3: (I) 49/363; (C) 117/366 Month 6: (I) 79/309; (C) 165/245 Month 9: (I) 99/278; (C) 199/194
 
Cameron et al, 2011  Continuation
Side effects or adverse events

Cover et al15  Pregnancy: (I) 3/561; (C) 2/600, not significant Continuation
Main effects model: HR 0.54 (0.44–0.68), p=0.00 Interaction model (including age): HR 0.75 (0.56–0.99), p=0.05 Side effects or adverse events
After first injection: (I) 161/539 (29.9%); (C) 197/580 (34.0%), p>0.05 After second injection: (I) 117/497 (23.5%); (C) 135/489 (27.6%), p>0.05 After third injection: (I) 88/473 (18.6%); (C) 98/432 (22.7%), p>0.05
After first injection: (I) 48/539 (8.9%); (C) 57/580 (9.8%), p>0.05 After second injection: (I) 33/497 (6.6%); (C) 47/489 (9.6%), p>0.05 After third injection: (I) 35/473 (7.4%); (C) 36/432 (8.3%), p>0.05
After first injection: (I) 33/539 (6.1%); (C) 8/580 (1.4%), p<0.05 After second injection: (I) 25/497 (5.0%); (C) 8/489 (1.6%), p<0.05 After third injection: (I) 38/473 (8.0%); (C) 5/432 (1.2%), p<0.05
After first injection: (I) 0/539 (0%); (C) 2/580 (0.3%), p>0.05 After second injection: (I) 2/497 (0.4%); (C) 0/489 (0%), p>0.05 After third injection: (I) 3/473 (0.6%); (C) 2/432 (0.5%), p>0.05 
Cover et al14  Pregnancy: (I) 0/650; (C) 1/649 Continuation
Side effects or adverse events
No serious adverse events were reported in either group.
After first injection: (I) 195/649 (30.1%); (C) 227/642 (35.4%), p=0.04 After second injection: (I) 130/615 (21.1%); (C) 155/598 (25/9%), p=0.05 After third injection: (I) 102/588 (17.4%); (C) 125/559 (22.4%), p=0.03
After first injection: (I) 18/195 (9.2%); (C) 50/227 (22.0%), p=0.00 After second injection: (I) 17/130 (13.1%); (C) 32/155 (20.6%), p=0.09 After third injection: (I) 16/102 (15.7%); (C) 28/125 (22.4%), p=0.20
After first injection: (I) 89/649 (13.7%); (C) 63/642 (9.8%), p=0.03 After second injection: (I) 52/615 (8.5%); (C) 55/598 (9.2%), p=0.65 After third injection: (I) 24/588 (4.9%); (C) 30/559 (5.4%), p=0.74
After first injection: (I) 0/89 (0%); (C) 0/63 (0%), p= – After second injection: (I) 0/52 (0%); (C) 0/55 (0%), p= – After third injection: (I) 0/29 (0%); (C) 1/30 (3.3%), p=0.32 
Kohn et al5  Pregnancy: (I) 0/200; (C) 3/200 Continuation

C, control;DMPA, depot medroxyprogesterone acetate; DMPASC, DMPA subcutaneous product; I, intervention;IRR, Interrater reliability; ISR, injection site reaction; RD, risk difference.